Gene Expression Profile of Increased Heart Rate in Shensongyangxin-Treated Bradycardia Rabbits

Figure 3

Effect of SSYX on the in human induced pluripotent stem cell-derived cardiomyocytes. Representative traces recorded from the absence (a) and presence of 0.5% SSYX (b), which showed the reduced current. (c) The peak current density-voltage relationship from two groups. The current density at 0 mV was decreased from  pA/pF in the model group to  pA/pF after SSYX administration (, ). The (d) steady-state activation curve, (e) inactivation curve, and (f) recovery curve in model and SSYX groups. The left shifted steady-state inactivation curve (, ) demonstrated that SSYX delayed the recovery time from inactivation. The data are presented as the mean ± SE; five cells were analyzed. Cells in the absence and presence of 0.5% SSYX are the same cells.

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