White Pepper and Piperine Have Different Effects on Pharmacokinetics of Puerarin in Rats
Figure 6
Plasma concentration-time profiles of puerarin after an intravenous administration of 40 mg/kg of puerarin to rats in the presence and absence of white pepper. The data are expressed as mean ± SD, . (●) Control (combined use with tween); (△) combined use with 125 mg/kg of pepper; (▲) combined use with 250 mg/kg of pepper. Insert shows the pharmacokinetics of puerarin at the first 25 min after intravenous administration.