Pharmacological Chaperone Design for Reducing Risk Factor of Parkinson’s Disease from Traditional Chinese Medicine

Figure 13

Ligand pathway of (a) tetrahydroxyazepanes, (b) N-methylmescaline, and (c) shihunine in GCase binding site by CAVER 3.0; starting point is the initial place for ligand binding; all generated channels are grouped to seven clusters.

(a)

(b)

(c)