The Effects of Loranthus parasiticus on Scopolamine-Induced Memory Impairment in Mice

Figure 1

(a) Effect of Loranthus parasiticus on escape latency (s) of 4 day-trial in Morris water maze test. Loranthus parasiticus (10, 50, and 100 mg/kg body weight, P.O.) and donepezil group (positive control; 1 mg/kg body weight, P.O.) treated 90 min before scopolamine administration. Scopolamine treated 30 min before water maze test. The values shown are the mean escape latency ± SD (^∗𝑃<0.05, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001 versus the scopolamine group). Control: control group, Sco: only scopolamine-treated group, and Sco + donpezil: scopolamine and donepezil treated group. Sco + Lo: scopolamine and Loranthus parasiticus treated group. (b) Swim speed of mice in Morris water maze test. Data represent means ± S.E.M. Control: control group, vehicle: only scopolamine-treated group, and donpezil: scopolamine and donepezil treated group. Lo: scopolamine and Loranthus parasiticus treated group. (c) Effect of Loranthus parasiticus (10, 50, and 100 mg/kg) on probe trial. Control: control group, vehicle: only scopolamine-treated group, and donpezil: scopolamine and donepezil treated group. Lo: scopolamine and Loranthus parasiticus treated group. Data represent means ± S.E.M. (^∗𝑃<0.05, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001 versus the scopolamine group).

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