The Effects of Platycodin D, a Saponin Purified from Platycodi Radix, on Collagen-Induced DBA/1J Mouse Rheumatoid Arthritis
Figure 2
Platycodin D inhibited changes in body weight in CIA mice. Values are expressed as means ± SD (); platycodin D 200 mg/kg treated mice showed significant () increases of body weight from 35 days after treatment, platycodin D 100 and 50 mg/kg treated mice showed significant () increases of body weight from 39 days after treatment, respectively (dot arrow). CIA, collagen-induced arthritis; −1IM, 1 day before immunization; IM, immunization (start of administration of test materials); 23, day of antigen challenge. All animals were fasted overnight before immunization and sacrifice (40 days after immunization).
