Effect of Integrated Cognitive Therapy on Hippocampal Functional Connectivity Patterns in Stroke Patients with Cognitive Dysfunction: A Resting-State fMRI Study

Table 3

Regions showing abnormal HFC in the Ischemic stroke patients with cognitive dysfunction comparing to HC in resting state.

Anatomical regions	Side	Cluster size	Peak coordinates (MNI)			Peak -score
			Middle temporal gyrus^a	R	82		33	−69	9	5.7958
Middle temporal gyrus^b	L	60	−51	−9	18	5.2177
Superior temporal gyrus^a	R	96	45	−33	−6	5.1406
Medial frontal gyrus^b	L	53	0	48	−6	5.0744
Insular cortex^a	L	48	−40	0	15	5.0512
Insular cortex^b	R	42	42	−6	−3	4.4423
Cerebellum anterior lobe^b	L	47	−6	−60	−9	4.7176
Cerebellum posterior lobe^b	L	46	−39	−57	−30	3.7787
Thalamus^a	L	35	−15	−12	9	−5.6475
Superior temporal gyrus^a	L	30	−24	3	−27	−4.7568
Thalamus^b	R	30	15	−3	3	−4.4357
Inferior frontal gyrus^b	R	85	36	18	24	−4.0718
Superior frontal gyrus^a	L	56	−33	27	30	−3.9030

Changes about functional connectivity of the left hippocampus with all other brain voxels in this study. ^bChanges about functional connectivity of the right hippocampus with all other brain voxels in this study.
, corrected for multiple comparison. R: right side; L: left side.