ERK1/2 and HIF1α Are Involved in Antiangiogenic Effect of Polyphenols-Enriched Fraction from Chilean Propolis

Figure 2

Effect of different concentrations of EEP or Pn on the HUVECs migration at 8 h. (a) Comparison of HUVECs with and without VEGF 10 µg/mL. (b) HUVECs treated with 1–15 µg/mL of EEP. (c) HUVECs treated with 1–15 µg/mL of Pn. (d) Migration in HUVECs treated with 1–15 µg/mL of EEP at 8 h. White lines represent the initial wound. ; ; (10 µg/mL versus VEGF); (15 µg/mL versus VEGF); (10 µg/mL versus VEGF); (10 µg/mL versus VEGF). C: control; V: vehicle; Pn: Pinocembrin.

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