Tissue Pharmacology of Da-Cheng-Qi Decoction in Experimental Acute Pancreatitis in Rats

Figure 2

Effects of different dose of DCQD on the inflammatory cytokines in lung, intestine, and pancreas tissues. Normal group = NG, model group = MG, low-dose group = LDG, medium-dose group = MDG, high-dose group = HDG. Rats ( = 6 per group) were given different dose of DCQD (6 g/kg in LDG, 12 g/kg in MDG, and 24 g/kg in HDG by body weight) 2 h after operation. After 24 h, the lung, intestine, and pancreas tissues were collected for examination of proinflammatory cytokines (IL-6 and TNF-α) and anti-inflammatory cytokines (IL-4 and IL-10). (a) Inflammatory cytokines in pancreas tissues. (b) Inflammatory cytokines in intestine tissues. (c) Inflammatory cytokines in lung tissues. The results are mean ± SE. and versus AP model group.

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