Evidence-Based Complementary and Alternative Medicine

Research Article

Animal Study on Primary Dysmenorrhoea Treatment at Different Administration Times

Table 1

Primary dysmenorrhoea mice model and administration.


	Normal	Model	3 d	6 d	Yuanhu

D1	Saline	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate
D1	Saline	Saline	Saline	Jingqian Zhitong Fang (JQF)	Yuanhu Zhitong tablet

D2	Saline	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate
D2	Saline	Saline	Saline	Jingqian Zhitong Fang (JQF)	Yuanhu Zhitong tablet

D3	Saline	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate
D3	Saline	Saline	Saline	Jingqian Zhitong Fang (JQF)	Yuanhu Zhitong tablet

D4	Saline	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate
D4	Saline	Saline	Jingqian Zhitong Fang (JQF)	Jingqian Zhitong Fang (JQF)	Yuanhu Zhitong tablet

D5	Saline	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate
D5	Saline	Saline	Jingqian Zhitong Fang (JQF)	Jingqian Zhitong Fang (JQF)	Yuanhu Zhitong tablet

D6	Saline	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate	Oestradiol benzoate
D6	Saline	Saline	Jingqian Zhitong Fang (JQF)	Jingqian Zhitong Fang (JQF)	Yuanhu Zhitong tablet

Note: the dosage of each drug was subcutaneous injection of oestradiol benzoate or saline (10 mg/kg); JQF (0.218 g/kg) and Yuanhu Zhitong tablet (0.218 g/kg) were intragastrically administered (0.02 mL/g).
For each group, moulding (saline or oestradiol benzoate) and drugs intervention (saline, JQF, or Yuanhu Zhitong tablet) were almost simultaneously performed in each day.