Antiosteoporotic Effects of Huangqi Sanxian Decoction in Cultured Rat Osteoblasts by Proteomic Characterization of the Target and Mechanism

Table 2

Summary of differentially expressed proteins in osteoblasts treated with HQSXD.

Spot; number^a	Protein; score^b	Matching; peptides (number)	Theoretical	Theoretical; Mr (Da)^c	Target protein	Species
1	70	6	9.27	39299	N-Formyl peptide receptor 2	Rattus norvegicus
3	67	7	5.65	54851	Alpha-spectrin	Rattus norvegicus
5	76	6	10.08	43712	Heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	Rattus norvegicus
6	173	12	5.57	29859	Prohibitin	Rattus norvegicus
7	67	4	4.59	12752	Transcription elongation factor B (SIII), polypeptide 1	Rattus norvegicus
8	70	11	4.98	127444	Chromosome segregation protein	Rattus norvegicus
9	101	4	6.91	17386	Nucleoside diphosphate kinase	Rattus norvegicus
10	84	12	8.86	48199	Mast cell carboxypeptidase A	Rattus norvegicus

Protein spot number according to Figure 3.
Protein scores were based on combined mass and mass/mass spectra from MALDI-TOF/TOF identification MS.
Theoretical molecular mass (Mr) and isoelectric point () from the NCBInr database.