Hepatoprotective Effect of Silymarin (Silybum marianum) on Hepatotoxicity Induced by Acetaminophen in Spontaneously Hypertensive Rats

Figure 1

Serum parameters of rats of all groups untreated, treated with APAP (3 g/kg, orally), and pretreated with SLM (200 mg/kg) of ALT (a), AST (b), ALP (c), γ-GT (d), and GLU (e) were determined 12 h after APAP intoxication. Results represent mean ± SEM of 12 rats per group. N + APAP versus N, N + SLM + APAP versus N + APAP, SHR + APAP versus SHR, SHR + SLM + APAP versus SHR + APAP, N versus SHR, and N + APAP versus SHR + APAP.

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