Hepatoprotective Effect of Silymarin (Silybum marianum) on Hepatotoxicity Induced by Acetaminophen in Spontaneously Hypertensive Rats

Figure 3

Histopathology of livers 12 hours after APAP injection. The livers were collected 12 hours from all groups after APAP administration (3 g/kg). Panels (a) and (b): N and SHR group that received only vehicle, respectively, (c) and (d): N and SHR group that received APAP, respectively. (e) and (f): N and SHR group pretreated with standard drug (SLM, 200 mg/kg per 7 days). Arrows indicate leukocyte infiltration. Sections were stained with H&E (magnification, ×40).

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(b)

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