Effect of α-Allocryptopine on Delayed Afterdepolarizations and Triggered Activities in Mice Cardiomyocytes Treated with Isoproterenol

Figure 6

Effect of ALL on steady-state activated and inactivated curve of . (a) The representative currents of activation and inactivation before and after being treated with Iso 30 nM and ALL 10 μM. (b and c) The steady-state activated curve of was shifted to negative potential, while the steady-state inactivated curve was shifted to positive potential following ISO treatment. Changes of steady-state (in)activated curves were reversed with 10 μM ALL treatment. and were shown in (d and e); and were shown in (f and g). , versus control myocytes; , versus myocytes with ISO treatment.

(a)

(b)

(c)

(d)

(e)

(f)

(g)