Oleanolic Acid Attenuates Insulin Resistance via NF-κB to Regulate the IRS1-GLUT4 Pathway in HepG2 Cells

Figure 8

Effect of OA on IRS1 protein expression with blocking of the expression of NF-κB. (a) Control; IR; P + Control; P + IR. (b) Control; IR; OA-25 μmol/L; OA-10 μmol/L; OA-5 μmol/L; P + IR; P + OA-25 μmol/L; P + OA-10 μmol/L; P + OA-5 μmol/L. The protein expression of IRS1 was measured via Western blotting as described in the text. The figures represent one of three experiments with similar results. compared with the Control group; compared with the IR group; ^* compared with the P + Control group; compared with the OA-25 μmol/L group; compared with the OA-10 μmol/L group; compared with the OA-5 μmol/L group.

(a)

(b)