Liquiritigenin Protects Rats from Carbon Tetrachloride Induced Hepatic Injury through PGC-1α Pathway

Figure 1

Liquiritigenin alleviated CCl4 caused the histological destruction of rat livers. Rats were treated with CCl4 and/or liquiritigenin for 8 weeks and liver sections were stained with Hematoxylin and Eosin. CCl4 treated rats had severe liver histological abnormity with widespread hepatocyte death, fatty accumulation, and immune cell infiltration, which was largely relieved by liquiritigenin.