Apoptosis-Inducing Activity of Marine Sponge Haliclona sp. Extracts Collected from Kosrae in Nonsmall Cell Lung Cancer A549 Cells

Figure 6

Haliclona sp. extract increased apoptosis. A549 cells were treated with Haliclona sp. extract for 48 h. Apoptotic cells were determined by Annexin V and PI staining and analyzed as described in Section 2. (a) Upper left, necrosis (%); upper right, late apoptosis (%); lower left, viable (%); lower right: early apoptosis (%). (b) The data showed total apoptosis (early apoptosis and late apoptosis).

(a)

(b)