Apoptosis-Inducing Activity of Marine Sponge Haliclona sp. Extracts Collected from Kosrae in Nonsmall Cell Lung Cancer A549 Cells

Table 1

Cytotoxicity of KO1304 series in A549 cells.

Sample name	IC30 (g/mL)	Sample name	IC30 (g/mL)
KO1304-101	>100	KO1304-207	>100
KO1304-102	>100	KO1304-208	>100
KO1304-103	>100	KO1304-221	>100
KO1304-105	>100	KO1304-223	>100
KO1304-107	>100	KO1304-301	>100
KO1304-201	>100	KO1304-302	>100
KO1304-203	>100	KO1304-303	>100
KO1304-204	>100	KO1304-326	>100
KO1304-205	>100	KO1304-328	68.3 ± 0.4
KO1304-206	>100	KO1304-329	>100

Each extract (titrated from 6.25 to 100 g/mL) was added to A549 cells for 48 h. IC₃₀ is the concentration at which 30% inhibition of cell viability is achieved.