Effects of Berberine on Cell Cycle, DNA, Reactive Oxygen Species, and Apoptosis in L929 Murine Fibroblast Cells

Table 1

Effect of berberine on DNA of L929 cells ().

Concentration (mg/mL)	Indicators
	TL (m)	TDNA (%)	TM (m)	Olive TM (m)
0	3.25 ± 0.46	0.37 ± 0.25	0.01 ± 0.01	0.18 ± 0.13
0.0025	8.67 ± 1.80	0.27 ± 0.20	0.02 ± 0.01	0.19 ± 0.11
0.0125	133.4 ± 18.50	11.73 ± 6.13	7.11 ± 3.76	6.14 ± 1.96
0.0250	240.1 ± 27.21	26.67 ± 10.55	35.97 ± 15.26	24.50 ± 9.31
Positive control	286.3 ± 53.71	84.12 ± 9.95	243.5 ± 64.27	131.88 ± 37.61

Visual scorings of DNA damage were based on the fluorescence intensity. TL: tail length; TDNA: tail DNA%; TM: tail moment; OTM: olive tail moment. Values are expressed as mean ± SD. compared with the control.