Berberine in Combination with Insulin Has Additive Effects on Titanium Implants Osseointegration in Diabetes Mellitus Rats

Figure 2

Summary of animal grouping and treatments. Animals were randomly allocated into five groups: healthy rats as control (HC) and 4 groups of diabetic rats including (1) no additional treatment, (2) insulin, (3) berberine, and (4) berberine + insulin therapies; the treatments were given to animals for 8 weeks until being sacrificed.