Berberine in Combination with Insulin Has Additive Effects on Titanium Implants Osseointegration in Diabetes Mellitus Rats

Figure 4

Fluorochrome double-labeling images of peri-implant osseointegration under microscopy at 10x (HC: healthy control; D: nontreated diabetic; I: insulin-treated diabetic; B: berberine-treated diabetic; IB: berberine + insulin-treated diabetic). Red was labeled by alizarin red at week 1 after surgery and green was labeled by calcein green at week 7 after surgery.