Berberine in Combination with Insulin Has Additive Effects on Titanium Implants Osseointegration in Diabetes Mellitus Rats

Table 1

Plasma glucose levels (mmol/L) of rats during the whole study.

Animal status	−3 weeks	0 days	1 week	4 weeks	8 weeks
Group HC	5.8 ± 0.7^1	6.4 ± 0.8^1	6.3 ± 0.8^1	6.6 ± 0.8^1	6.7 ± 0.7^1
Group D	6.2 ± 0.7^1	27.1 ± 2.2^2	24.0 ± 2.4^5	29.1 ± 1.9^3	25.4 ± 1.2^3
Group I	6.1 ± 0.8^1	26.8 ± 3.0^2	11.2 ± 1.8^3	8.7 ± 1.2^1	7.1 ± 0.6^1
Group B	6.2 ± 0.7^1	26.8 ± 3.7^2	20.1 ± 1.6^4	17.5 ± 2.2^2	11.2 ± 1.3^2
Group IB	6.3 ± 0.6^1	24.4 ± 1.4^2	8.7 ± 1.7^2	6.4 ± 1.2^1	6.7 ± 0.9^1

Means with identical superscripts in a given column are not statistically significant at the 5% alpha level.