Review Article

The Effects of Acupuncture on Cerebral and Muscular Microcirculation: A Systematic Review of Near-Infrared Spectroscopy Studies

Table 2

Study designs and populations. Summary of objectives, study design types, and populations involved in the reviewed articles.

PurposeStudy designPopulationType (Pop.)

Compare body (A) versus body & scalp (B) acupuncture for stroke [28] Comparative = 20: A/B = 10/10, f : m = 4 : 6/3 : 7, by intervention, age range 41–72/42–75Stroke

Electric moxibustion at (a) Baihui GV 20 or (b) Shenque CV 8 for healthy subjects [29] Comparative = 20 (a) = 10, f/m = 5/5, age range 25–53; (b) = 10, f/m = 5/5, age range 27–51Healthy

Changes in regional cerebral oxygenation after various methods of acupuncture [27] Observational = 88: f/m = 50/38, age range 19–38 Healthy

Effects of manual and laser acupuncture on cerebral oxygenation [30] Observational = 3, male, ages 25, 50, and 70Healthy

P-STIM auricular electroacupuncture [32] Observational = 2, female, ages 23 and 27Healthy

Regional cerebral oxygenation changes during and after acupuncture [33] Observational = 12: f/m = 4/8, age range 26–41Healthy

Cerebral parameters of healthy subjects after stimulating acupuncture points associated with intracranial pressure [38] Observational = 34, f/m = 24/10, age range 20–35
Intensive care patient after severe head injury ( = 1, age 15)
Healthy

Acupuncture for cerebrovascular dementia [34] Case study = 1, age 77, femaleCerebrovascular dementia

Changes in regional cerebral oxygen saturation in neonates undergoing laser acupuncture at Hegu LI 4 [37] Observational = 20: f/m = 8/12, age < 1Neonates

Effects on brain activity of trigger point (TP) versus nontrigger point stimulation and de-qi induction [35] Comparative = 20: f/m = 5/15, age range: 19–30
TP first: f/m = 1/9, non-TP first: f/m = 3/7
Healthy

Effects of acupuncture at Hegu LI 4 on central frontal cortex [31] Observational = 16, f/m = 9/7, age range 19–45Healthy

Compare blood oxygenation in stimulation region and distant region in trapezius muscle [40] Controlled = 19: AS = 9: f/m = 7/2 age 36
no AS = 10: f/m = 7/3, age 29
Healthy, acupuncture-experienced

Tender dry point needling for neck pain (katakori) Experiment I [41] Controlled = 9: f/m = 7/2, age range 22–48; control = 4: f/m = 0/4, age range 25–27 Neck pain

Tender dry point needling for neck pain (katakori) Experiment II [41] Observational = 13: f/m = 8/5, age range 24–48 Neck pain

Effect of acupressure at Xiyangguan GB 33 on regional oxygen saturation of deeper knee tissues [39] Observational = 12: f/m = 5/7, age: 23.8 ± 1.6 yrsHealthy

Effect of laser needle stimulation at acupuncture point on blood flow and oxygenation in forearm [42] Randomized
Double-blinded Placebo-controlled
= 33: age 26.6 3.4
laser/no-laser = 18/15
Healthy

Near-infrared optical imaging to evaluate efficacy of acupuncture on peripheral tissue perfusion [36] Observational = 2: f/m = 1/1, age 20/39 Healthy