Research Article

Ointment of Brassica oleracea var. capitata Matures the Extracellular Matrix in Skin Wounds of Wistar Rats

Table 1

Effects of Brassica oleracea (balsam and ointment) and Helianthus annuus (sunflower oil) on the area and the rate of wound contraction in rats evaluated every 4 days for 20 days of treatment.

Day Area/contractionBalsamOintmentSunflower Control

0 (mm2)121.35 ± 1.11122.23 ± 1.06120.56 ± 1.77120.67 ± 1.99
WCI (%)0.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.00

4 (mm2)109.85 ± 5.43109.54 ± 3.32118.18 ± 4.32117.46 ± 2.54
WCI (%)9.47 ± 2.0210.12 ± 2.321.967 ± 1.282.66 ± 1.42

8 (mm2)75.15 ± 4.3265.76 ± 7.1478.32 ± 3.2388.87 ± 5.43
WCI (%)38.07 ± 4.5646.19 ± 5.4535.03 ± 4.3126.35 ± 4.20

12 (mm2)42.76 ± 6.3242.56 ± 5.5450.46 ± 4.5560.65 ± 4.65
WCI (%)56.52 ± 5.4365.18 ± 5.4358.14 ± 4.9849.73 ± 5.21

16 (mm2)10.13 ± 3.138.33 ± 4.3217.65 ± 3.1220.32 ± 6.32
WCI (%)91.65 ± 4.8790.18 ± 4.7985.36 ± 4.4383.16 ± 4.43

20 (mm2)0.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.00
WCI (%)100.00 ± 0.00100.00 ± 0.00100.00 ± 0.00100.00 ± 0.00

Data are reported as mean ± S.D. : wound area, WCI: wound contraction index; balsam: Brassica oleracea oil; ointment: Brassica oleracea lanolin; sunflower oil: Helianthus annuus; control: 0.9% saline; , statistically different compared to the control group; , statistically different compared to sunflower oil. Kruskal-Wallis test.