Ointment of Brassica oleracea var. capitata Matures the Extracellular Matrix in Skin Wounds of Wistar Rats
Table 2
Levels of total collagen and glycosaminoglycans in the scar tissue of rats treated with Brassica oleracea (balsam and ointment) and Helianthus annuus (sunflower oil) and evaluated every 4 days for 20 days of treatment.
Treatments
Day 0
Day 4
Day 8
Day 12
Day 16
Day 20
Collagen (µg/g protein)
Balsam
512.11 ± 46.13
200.34 ± 43.23
277.63 ± 30.81
305.23 ± 27.23
594.58 ± 9.07
493.09 ± 5.70
Ointment
502.45 ± 39.32
201.23 ± 46.45
299.53 ± 33.27
310.45 ± 32.43
581.66 ± 34.33
421.82 ± 54.11
Sunflower
512.26 ± 50.25
200.34 ± 44.32
210.42 ± 42.22
315.35 ± 36.32
519.28 ± 42.82
402.17 ± 29.16
Control
510.25 ± 59.24
199.43 ± 45.32
203.72 ± 51.03
301.34 ± 34.67
520.47 ± 43.91
400.34 ± 32.14
Glycosaminoglycans (µg/g protein)
Balsam
39.46 ± 7.33
52.34 ± 6.23
88.52 ± 10.62
70.43 ± 7.23
71.23 ± 8.18
47.36 ± 9.02
Ointment
37.28 ± 8.07
51.34 ± 5.32
75.23 ± 8.30
73.23 ± 8.34
66.80 ± 10.37
42.25 ± 8.16
Sunflower
39.36 ± 6.52
53.45 ± 5.23
59.21 ± 8.25
59.55 ± 7.32
60.00 ± 7.54
56.51 ± 6.10
Control
40.35 ± 5.12
50.72 ± 5.23
58.11 ± 9.05
59.20 ± 6.23
60.19 ± 7.54
56.51 ± 6.10
Balsam: Brassica oleracea, oil; ointment: Brassica oleracea lanolin; sunflower oil: Helianthus annuus; control: 0.9% saline; denotes a statistical difference compared to the control group; denotes a statistical difference compared to the sunflower oil group. Day 0 represents the unharmed tissue. Data are represented as mean and standard deviation (mean ± S.D.). Kruskal-Wallis test.
