Bavachalcone Enhances RORα Expression, Controls Bmal1 Circadian Transcription, and Depresses Cellular Senescence in Human Endothelial Cells

Figure 3

Bavachalcone-enlarged expression amplitude of the circadian gene Bmal1. After HUVECs were treated with 50% serum shock for 1 h, the medium was replaced with 10% serum DMEM with or without 20 μmol/L bavachalcone. The mRNA expression levels at the indicated time were measured using semiquantitative (a) and real-time quantitative PCR (b) ( each). Data are expressed as the mean ± SD. versus vehicle control.

(a)

(b)