Bavachalcone Enhances RORα Expression, Controls Bmal1 Circadian Transcription, and Depresses Cellular Senescence in Human Endothelial Cells

Figure 4

Bavachalcone-delayed senescence of HUVEC. (a and b) HUVECs were passaged from the 10th to the 40th generation and cultured with or without bavachalcone. Subsequently, the cells were dyed using a β-galactosidase senescence assay kit. The percentage of senescent cells was obtained by counting more than 500 cells in each sample ( each). Data are expressed as the mean ± SD. versus p10 passage vehicle control. versus p40 passage vehicle control.

(a)

(b)