Bavachalcone Enhances RORα Expression, Controls Bmal1 Circadian Transcription, and Depresses Cellular Senescence in Human Endothelial Cells

Table 1

Screening list using RORα1 luciferase reporter (dose = 10 mol/L).

Chemical names	Chemical structures	CAS number	Molecular weight	Expression (folds/control, , mean ± SD)
Bavachalcone		28448-85-3	324.4	2.2295 ± 0.0785
Isobavachalcone		20784-50-3	324.4	0.9188 ± 0.1373
Bavachin		19879-32-4	324.4	1.0106 ± 0.0721
Isobavachin		31524-62-6	324.4	0.9988 ± 0.0472
Glabranin		41983-91-9	324.4	1.0901 ± 0.0405
Mulberrin		62949-79-5	422.5	1.2416 ± 0.1792
Psoralidin		18642-23-4	336.3	0.9612 ± 0.0415
Icariin		489-32-7	676.7	1.2514 ± 0.2206
Corylin		53947-92-5	320.3	0.9953 ± 0.0188
Olivil		2955-23-9	376.4	0.9471 ± 0.1459
Psoralen		66-97-7	186.2	1.0530 ± 0.0497
Angelicin		523-50-2	186.2	0.9476 ± 0.0542
8-Methoxypsoralen		298-81-7	216.2	1.0068 ± 0.0182
Pinoresinol diglucoside		63902-38-5	682.7	1.1309 ± 0.0533
Eleutheroside E		39432-56-9	742.7	1.0357 ± 0.0305
Catechin		7295-85-4	290.3	1.0800 ± 0.0681
Coniferin		531-29-3	342.3	1.3680 ± 0.1221
Genipin		6902-77-8	226.2	1.0714 ± 0.0847
Geniposide		24512-63-8	388.4	0.9631 ± 0.0851
Aucubin		479-98-1	346.3	0.9624 ± 0.2046