Effect of a Traditional Herbal Prescription, Kyung-Ok-Ko, on Male Mouse Spermatogenic Ability after Heat-Induced Damage

Figure 1

Effect of KOK on histological changes in testes of mice with heat stress-induced infertility. H&E staining was performed using testicular tissue after heat stress and/or KOK treatment for 5 weeks. Representative photomicrographs are shown in (a), and the mean optical density of seminiferous tubules was measured in (b). (A) Normal group; (B) heat stress group; (C–E) heat stress and KOK treatment at 0.25, 0.50, and 2.00 g/kg, respectively. Scale bar = 200 μm. Each column represents the mean ± SEM (). compared with the normal group; compared with the heat stress group.

(a)

(b)