Induction of Thioredoxin Reductase 1 by Korean Red Ginseng Water Extract Regulates Cytoprotective Effects on Human Endothelial Cells

Figure 3

KRG-treated expression of TrxR1 is mediated by EpRE/ARE. Cells transfected with an EpRE/ARE-luciferase construct were stimulated with various concentrations of KRG for 6 h (a) and with 1 mg/mL of KRG for various time intervals (b). The lysates were mixed with a luciferase substrate and a luminometer was used to measure luciferase activity. Data represent the mean ± S.D-values of 3 independent experiments.

(a)

(b)