Electroacupuncture Pretreatment at GB20 Exerts Antinociceptive Effects via Peripheral and Central Serotonin Mechanism in Conscious Migraine Rats

<div>Effect of EA pretreatment on 5-HT level of endogenous pain modulatory system in migraine rats. (a) High-performance liquid chromatography chromatograms of extracted samples. Red curve indicates internal standards; black curve indicates samples. 5-HT was eluted at around 18 min. 5-HT concentrations in the periaqueductal gray (PAG), rostroventromedial medulla (RVM), and trigeminal nucleus caudalis (TNC) were measured by high-performance liquid chromatography (b, c, d). 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Evidence-Based Complementary and Alternative Medicine

fig5

Figure 5

Figure 5: Electroacupuncture Pretreatment at GB20 Exerts Antinociceptive Effects via Peripheral and Central Serotonin Mechanism in Conscious Migraine Rats 

Figure 5 | Electroacupuncture Pretreatment at GB20 Exerts Antinociceptive Effects via Peripheral and Central Serotonin Mechanism in Conscious Migraine Rats 