Evaluation of the In Vivo Therapeutic Effects of Radix Paeoniae Rubra Ethanol Extract with the Hypoglycemic Activities Measured from Multiple Cell-Based Assays

Figure 3

Insulinotropic effects of four constituents of Radix Paeoniae Rubra on glucose-stimulated insulin secretion of BRIN-BD11 cells. The insulinotropic effects of (a) paeoniflorin, (b) pentagalloylglucose, (c) paeonol, and (d) PEF on BRIN-BD11 cells under hyperglycemic conditions (16.7 mM glucose). Data are presented as the mean ± SEM (–8/group). and when compared with insulin levels under hyperglycemic conditions (16.7 mM glucose).

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