Biological Evaluation and Docking Analysis of Daturaolone as Potential Cyclooxygenase Inhibitor

Figure 2

Effect of compound 1 on carrageenan-induced paw oedema. Compound 1 (1.0–30.0 mg/kg) or diclofenac (1.0–30.0 mg/kg) was administered intraperitoneally (i.p.) 30 min before the subcutaneous injection of 50 μL of 1% carrageenan and paw swelling measured at 4 h. Values reported as percentage (%) of inhibition of paw oedema are expressed as log dose (mg/kg) ± SEM (). , , and .