Biological Evaluation and Docking Analysis of Daturaolone as Potential Cyclooxygenase Inhibitor

Figure 4

2D and 3D model of compound 1 in the binding site of COX-1 ((a) and (d)) and COX-2 ((b) and (e)). Half-moon indicates the hydrophobic interactions. ((c) and (f)) Superimposition of compound 1 (colored by green) and diclofenac (colored by cyan) in the binding site of COX-1 (c) and COX-2 (f) enzyme (colored by red).

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(b)

(c)

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(f)