Gigantol Inhibits Epithelial to Mesenchymal Process in Human Lung Cancer Cells

Figure 2

Effect of gigantol on human lung cancer cell H460 cytotoxicity. (a) H460 cells were treated with various concentrations (0–50 μM) of gigantol for 24 h, and cell viability was measured by the MTT assay. The viability of untreated control cells was represented as 100%. (b) H460 cells were treated with various concentrations (0–50 μM) of gigantol for 24 h, and apoptotic cell death was evaluated using Hoechst 33342 nuclear staining dye. The percentages of cells undergoing apoptosis were calculated comparing to the untreated control cells. (c) The fluorescence images were captured after staining with either Hoechst 33342 or propidium iodide (PI) (scale bar is 50 μm). The data represent mean ± SE (). versus untreated control cells.

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