Effects of Yishen Pinggan Recipe on Renal Protection and NF-κB Signaling Pathway in Spontaneously Hypertensive Rats

Figure 3

Influence of YPR on expressions of inflammatory cytokines including IL-1β (a), IL-6 (b), and TNF-α (c). (a), (b), and (c) are immunohistologic results of IL-1β, IL-6, and TNF-α: (A) WKY group, (B) SHR group, (C) Bena group, and (D) YPR group. (d) Compared with the WKY group ; compared with the SHR group , ; compared with the Bena group ; compared with the WKY group, in the SHR group, expression levels of IL-1β, IL-6, and TNF-α in the renal tissues were significantly increased. In the YPR group, IL-1β, IL-6, and TNF-α expression levels in renal tissues were significantly decreased and no significant difference was found when compared with the WKY group.

(a) IL-1β

(b) IL-6

(c) TNF-α

(d) Quantified