Epigenetic Profiling of H3K4Me3 Reveals Herbal Medicine Jinfukang-Induced Epigenetic Alteration Is Involved in Anti-Lung Cancer Activity

Figure 1

Treatment with JFK induces proliferation inhibition and nuclear morphology alteration in A549 cells. (a) A549 cells were treated with JFK drug serums from day 3, day 7, and day 14, respectively (, ). (b) A549 cells were treated with JFK drug serum from day 14 for 12 h, 24 h, 48 h, 72 h, 96 h, and 120 h, respectively (, , , and ). (c, d) A549 cells were stained with DAPI for detecting nucleus changes using CLSM. Scale bar: 25 μm.

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