The Zuo Jin Wan Formula Induces Mitochondrial Apoptosis of Cisplatin-Resistant Gastric Cancer Cells via Cofilin-1

Figure 4

ZJW induces dephosphorylation of p-cofilin-1 in BGC823/DDP and SGC7901/DDP cells. (a) Western blot assayed p-cofilin-1 expressing level in DDP-sensitive cells and DDP resistant cells. (b) and (c) P-cofilin-1 expressing level changes after being treated with 1 μg/mL DDP in four gastric cancer cells for 24 h. (d) The combination of DDP and ZJW induces the dephosphorylation of p-cofilin-1 in BGC823/DDP and SGC7901/DDP cells.

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