Inhibitory Effect of Valencene on the Development of Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice

Figure 3

Effects of valencene on DNCB-induced changes in (a, b) proinflammatory cytokines and (c) IgE. (a) Levels of IL-1β, IL-4, IL-6, IL-13, and TNF-α in (a) skin and (b) splenic tissue were determined by commercial ELISA kits. (c) Serum was isolated from each group of mice after sacrifice, and the serum level of IgE was determined using ELISA. Data were expressed as means ± SDs ( per experiment). versus DNCB alone.

(a)

(b)

(c)