Flavonoids and Sesquiterpene Lactones from Artemisia absinthium and Tanacetum parthenium against Schistosoma mansoni Worms

Table 1

In vitro effects of crude extracts of A. absinthium (AA) and T. parthenium (TP) against S. mansoni adult worms.

Groups	Incubation period (h)	Dead worms	Decrease of motor activity		Worms with tegumental alteration
			Slight	Significant		Slight
	24	0	0	0	0	0
	48	0	0	0	0	0
	72	0	0	0	0	0
0.5% DMSO	24	0	0	0	0	0
	48	0	0	0	0	0
	72	0	0	0	0	0
	24	100	0	100	0	100
	48	100	0	100	0	100
	72	100	0	100	0	100
AA
200 µg/mL	24	100	0	100	0	100
	48	100	0	100	0	100
	72	100	0	100	0	100
100 µg/mL	24	0	0	0	0	0
	48	100	0	100	0	100
	72	100	0	100	0	100
50 µg/mL	24	0	0	0	0	0
	48	100	0	100	0	100
	72	100	0	100	0	100
25 µg/mL	24	0	0	0	0	0
	48	0	0	0	0	0
	72	20	0	20	0	20
12.5 µg/mL	24	0	0	0	0	0
	48	0	0	0	0	0
	72	0	0	0	0	0
TP
200 µg/mL	24	100	0	100	0	100
	48	100	0	100	0	100
	72	100	0	100	0	100
100 µg/mL	24	100	0	100	0	100
	48	100	0	100	0	100
	72	100	0	100	0	100
50 µg/mL	24	100	0	100	0	100
	48	100	0	100	0	100
	72	100	0	100	0	100
25 µg/mL	24	0	0	0	0	0
	48	0	0	0	0	0
	72	50	0	50	0	50
12.5 µg/mL	24	0	0	0	0	0
	48	0	0	0	0	0
	72	0	0	0	0	0

relative to 20 worms investigated.
1640.
at concentration of 5 µM.