Qingxuan Jiangya Decoction Mitigates Renal Interstitial Fibrosis in Spontaneously Hypertensive Rats by Regulating Transforming Growth Factor-β1/Smad Signaling Pathway

Figure 3

Effect of QXJYD treatment on the expression of collagen fiber in SHRs. (a) Representative image of Masson trichrome staining of kidney. (b) The Masson trichrome-positive tubulointerstitial area (blue) relative to the whole area from 6 random kidney fields was evaluated. Data are represented as the mean SEM (). Immunohistochemical analysis was performed to determine the protein expression of Collagen I (c), Collagen III (d), and Collagen IV (e) in renal interstitial from each group (). Images were representatives taken at a magnification of 40x. (f) Quantification of the mean expressions of Collagen I, Collagen III, and Collagen IV protein. All values were represented as the mean SD; compared to WKY group and compared to SHR group.

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