Erchen Decoction and Linguizhugan Decoction Ameliorate Hepatic Insulin Resistance by Inhibiting IRS-1Ser307 Phosphorylation In Vivo and In Vitro

<div>Effect of ECD and LGZGD on hepatic morphology and pathological changes. Histological micrograph of liver specimen from ND, HFD, HFD + ROG, HFD + ECD, and HFD + LGZGD rats (H&amp;E staining and Oil Red O staining, magnification ×100). (a) ND group; (b) the HFD group; (c) the HFD + ROG group; (d) the HFD + ECD group; (e) the HFD + LGZGD group. The major histopathological change induced by HFD in rat’s liver was hepatocyte steatosis (filled arrow) with inflammation (open pentagram) and ballooning (white arrow).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 2: Erchen Decoction and Linguizhugan Decoction Ameliorate Hepatic Insulin Resistance by Inhibiting IRS-1Ser307 Phosphorylation In Vivo and In Vitro 

Figure 2 | Erchen Decoction and Linguizhugan Decoction Ameliorate Hepatic Insulin Resistance by Inhibiting IRS-1Ser307 Phosphorylation In Vivo and In Vitro 