Platonia insignis Mart., a Brazilian Amazonian Plant: The Stem Barks Extract and Its Main Constituent Lupeol Exert Antileishmanial Effects Involving Macrophages Activation

Figure 9

Production of nitrite in murine peritoneal macrophages treated with EtOH-Ext (a), Hex-F (b), and Lupeol (c). Murine peritoneal macrophages were treated and then incubated for 24 h. After this period, supernatants were mixed with Griess’ reagent in equal parts. LPS, bacterial lipopolysaccharide (2 mg/mL). Data are presented as mean ± SEM of three experiments carried out in triplicate. versus control; versus control; versus control.

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