Yangyin Runchang Decoction Improves Intestinal Motility in Mice with Atropine/Diphenoxylate-Induced Slow-Transit Constipation

Figure 3

Pathological changes in the mice. The histopathological analysis identified mucosal damage and inflammatory cell infiltration into the mucosa in the MC group; however, these changes were ameliorated in the L-YRD and H-YRD groups. SCF levels and the number of c-kit-positive cells were lower in the MC group than they were in the NC group; however, they were preserved in the YRD treatment groups. Arrows indicate the positive cells. The IOD of c-kit was lower in the MC group than it was in the NC group ( indicates P < 0.01); however, it was higher in the L-YRD and H-YRD groups than it was in the MC group ( indicates P < 0.05). The IOD of SCF was lower in the MC group than it was in the NC group, and it was higher in the L-YRD group than it was in the MC group ( indicates P < 0.05).