Cryptotanshinone Regulates Androgen Synthesis through the ERK/c-Fos/CYP17 Pathway in Porcine Granulosa Cells

Figure 3

The protein expression of CYP17 in cells after exposure to PD98059 (values are mean ± SEM). (a) The protein level of CYP17 when PD98059 was 0 μM, 1 μM, 3 μM, 10 μM, and 25 μM and the culture time was 24 h. versus 0 μM (one-way ANOVA). (b) The protein expression of CYP17 when the culture time was 0 h, 1 h, 5 h, 24 h, 48 h, and 72 h with 10 μM PD98059. versus 0 h (one-way ANOVA). All experiments were repeated at least three times.

(a)

(b)