Cryptotanshinone Regulates Androgen Synthesis through the ERK/c-Fos/CYP17 Pathway in Porcine Granulosa Cells

Figure 6

The effects on protein expression of P-ERK1/2 in pGCs treated with cryptotanshinone (values are mean ± SEM). (a) The protein level of P-ERK1/2 in pGCs when treated with 0 μM, 1 μM, 10 μM, 25 μM, and 50 μM cryptotanshinone for 24 h. versus control I (Cry− and PD−); versus control II (Cry− and PD+) (one-way ANOVA). (b) The protein level of P-ERK1/2 in androgen excess cells when treated with 10 μM cryptotanshinone for 3 h, 6 h, 18 h, and 24 h. versus Cry− (one-way ANOVA). All experiments were repeated at least three times.

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