Pharmacokinetic Comparison of 20(R)- and 20(S)-Ginsenoside Rh1 and 20(R)- and 20(S)-Ginsenoside Rg3 in Rat Plasma following Oral Administration of Radix Ginseng Rubra and Sheng-Mai-San Extracts

Table 2

The extraction recovery, precision, and accuracy of 20(R)-Rh1, 20(S)-Rh1, 20(R)-Rg3, and 20(S)-Rg3 in rat plasma .

Analytes	Spiked concentration (ng/mL)	Recovery (%)	RSD (%)	Intraday		Interday
				Precision RSD (%)	Accuracy (%)	Precision RSD (%)	Accuracy (%)
20(R)-Rh1	1.0	81.0	9.6	3.9	105.7	5.3	104.2
	10.0	82.4	2.3	3.3	96.2	4.0	101.3
	90.0	80.9	6.6	2.1	104.5	3.7	99.6
20(S)-Rh1	1.0	85.1	7.9	5.6	94.9	11.7	95.0
	10.0	81.3	3.7	5.2	105.4	5.9	106.1
	90.0	81.2	5.9	8.4	102.1	3.1	103.3
20(R)-Rg3	1.0	83.3	9.2	7.2	109.5	6.7	107.6
	10.0	70.4	3.1	4.4	103.9	6.1	102.6
	90.0	70.9	8.3	3.3	102.7	10.3	98.7
20(S)-Rg3	1.0	83.8	2.0	2.5	89.2	8.7	92.4
	10.0	71.7	2.1	7.1	96.7	7.5	95.9
	90.0	72.6	6.8	6.1	97.4	9.8	94.8