Pharmacokinetic Comparison of 20(R)- and 20(S)-Ginsenoside Rh1 and 20(R)- and 20(S)-Ginsenoside Rg3 in Rat Plasma following Oral Administration of Radix Ginseng Rubra and Sheng-Mai-San Extracts

Table 4

Pharmacokinetic parameters of 20(R)-Rh1, 20(S)-Rh1, 20(R)-Rg3, and 20(S)-Rg3 in male rats after oral administration of SMS and Radix Ginseng Rubra extracts (1.35 mL/100 g).

Herb extract	Pharmacokinetic parameters	Ginsenosides
		20(R)-Rh1	20(S)-Rh1	20(R)-Rg3	20(S)-Rg3
SMS	(h)	0.0833	1.50	1.50	1.50
	(ng/mL)		1
	1/2 (h)
	(ng/mL)
	(ng/mL)
	Radix Ginseng Rubra	(h)	0.50	0.50	0.50	0.50
(ng/mL)
1/2 (h)
(ng/mL)
(ng/mL)

Mean ± SD. , , compared with those from Radix Ginseng Rubra extract.