Research Article
In Vivo and In Vitro Hepatoprotective Effects of Geranium koreanum Methanolic Extract via Downregulation of MAPK/Caspase-3 Pathway
Figure 6
GK attenuated mRNA expression level of MAPK (ERK, JNK, and p38) in the liver tissue. In NaAsO2 (10 mg/kg) treated mice liver tissue, mRNA expression levels of ERK, JNK, and p38 were significantly upregulated while cotreatment with GK (20 mg/kg) markedly downregulated expression level. when compared with the control and when compared with NaAsO2 treated. Data are expressed as mean ± SEM.