The Anti-Inflammatory Effect of Guchangzhixie-Pill by Reducing Colonic EC Cell Hyperplasia and Serotonin Availability in an Ulcerative Colitis Rat Model

Figure 2

Representative hematoxylin-eosin stained sections of colonic specimens harvested from the control rats (a), from the TNBS-induced UC rats (b), from the TNBS-induced UC rats given pCPA (c), and from the TNBS-induced UC rats given GCZX-pill 9.6 g/kg (d), scale bar = 50 μm; the epithelial degeneration, neutrophilic infiltration, and submucosal edema are indicated by arrows. The effect of GCZX-pill on MPO activity in TNBS-induced UC rats is shown in (e). Data are shown as mean ± SEM ( = 12 per group). < 0.01 versus the control rats; < 0.05 and < 0.01 versus the UC rats; one-way ANOVA followed by Bonferroni’s posttest.

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