Evidence-Based Complementary and Alternative Medicine

Research Article

The Root Aqueous Extract of Entada africana Guill. et Perr. (Mimosaceae) Inhibits Implant Growth, Alleviates Dysmenorrhea, and Restores Ovarian Dynamic in a Rat Model of Endometriosis

Table 2

Number of antral follicles, corpus luteum, and luteinized unruptured follicles in rat ovaries.
 3-day treatment7-day treatment14-day treatment
AntralCL/ratLUFs/ratAntralCL/ratLUFs/ratAntralCL/ratLUFs/rat
follicles/ratfollicles/ratfollicles/rat
SHAM
Control
Micro
EA 127.5
EA 255
EA 510
Results are presented as mean ± SEM; ; , , and versus SHAM; , , and versus control; treated groups were compared to SHAM and to control within the same treatment period using one-way ANOVA + Tukey’s multiple comparison test; SHAM: sham operated animals; control: animals with endometriosis receiving the vehicle; micro: animals with endometriosis treated with the reference substance Microgynon; EA: animals with endometriosis receiving the aqueous extract of Entada africana at 127.5, 255, or 510 mg/kg BW/day; CL: corpus luteum; LUFs: luteinized unruptured follicles.